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Name of Notes : – Gene Therapy Lecture Note
Gene therapy is when DNA is introduced into a patient to treat a genetic disease. The new DNA usually contains a functioning gene to correct the effects of a disease-causing mutation.
- Gene therapy uses sections of DNA (usually genes) to treat or prevent disease.
- The DNA is carefully selected to correct the effect of a mutated gene that is causing disease.
- The technique was first developed in 1972 but has, so far, had limited success in treating human diseases.
- Gene therapy may be a promising treatment option for some genetic diseases, including muscular dystrophy and cystic fibrosis.
- There are two different types of gene therapy depending on which types of cells are treated:
- Somatic gene therapy: transfer of a section of DNA to any cell of the body that doesn’t produce sperm or eggs. Effects of gene therapy will not be passed onto the patient’s children.
- Germline gene therapy: transfer of a section of DNA to cells that produce eggs or sperm. Effects of gene therapy will be passed onto the patient’s children and subsequent generations.
Modules / Lectures
- In vivo GeneTherapy
- Viral vectors
- Cancer Gene Therapy
- Gene Therapy and diseases-I
- Gene Therapy and diseases-II